Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders

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Assignment: Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders

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Gastrointestinal (GI) and hepatobiliary disorders affect the structure and function of the GI tract. Many of these disorders often have similar symptoms, such as abdominal pain, cramping, constipation, nausea, bloating, and fatigue. Since multiple disorders can be tied to the same symptoms, it is important for advanced practice nurses to carefully evaluate patients and prescribe a treatment that targets the cause rather than the symptom.
Once the underlying cause is identified, an appropriate drug therapy plan can be recommended based on medical history and individual patient factors. In this Assignment, you examine a case study of a patient who presents with symptoms of a possible GI/hepatobiliary disorder, and you design an appropriate drug therapy plan.
To Prepare
• Review the case study assigned by your Instructor for this Assignment
• Reflect on the patient’s symptoms, medical history, and drugs currently prescribed.
• Think about a possible diagnosis for the patient. Consider whether the patient has a disorder related to the gastrointestinal and hepatobiliary system or whether the symptoms are the result of a disorder from another system or other factors, such as pregnancy, drugs, or a psychological disorder.
• Consider an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed

CASE STUDY:

APA format, 12 font, times new roman, 4 sources,

Patient HL comes into the clinic with the following symptoms: nausea, vomiting, and diarrhea. The patient has a history of drug abuse and possible Hepatitis C. HL is currently taking the following prescription drugs:
Synthroid 100 mcg daily
Nifedipine 30 mg daily
Prednisone 10 mg daily

Instructor/Facilitator help:
1. One short paragraph on three differential diagnoses. Do not just say “symptoms are vague, no diagnoses possible, I will just do further assessment.”
Subjective & Objective information are intentionally provided vague (as a clinical case) so that you can develop a couple of pharmacological cases & discuss.
2. One short paragraph EACH on how you will pharmacologically treat the three diagnoses you listed (Pharmacological Plan).
3. Include NEWER AGENTS of cure for hepatitis C infection. Discuss how these NEWER hepatitis C drugs of CURE work.
4. Discuss mechanism of action, therapeutic applications and key kinetics of these agents.
5. One short paragraph each on Synthroid, Nifedipine (a peripheral calcium channel blocker) & prednisone an anti-inflammatory immune suppressor (pharmacological information) and why patient was on these drugs, based on your objective & assessment.
6. Long discussions/stories of no relevance to advanced pharmacology will carry no value with this project.
7. Include peer reviewed, scholarly articles of past 4 years as reference.
8. A conclusion with clinician level pharmacology in focus.
Clinician level discussion is expected.

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