Cellulitis

Can Use this info as a guide- I believe he has CELLULITIS

 

Key Points

  1. Cellulitis is a spreading infection of the skin extending to involve the subcutaneous tissues. Many conditions present similarly to cellulitis — always consider differential diagnoses
  2. The typical presenting features of all skin infections include soft tissue redness, warmth and swelling, but other features are variable
  3. Allergic reactions and contact dermatitis are frequently misdiagnosed as cellulitis. If there is itch and no tenderness, cellulitis is unlikely

Background

Cellulitis

  • The most common causes are Group A streptococcus (GAS) and Staphylococcus aureus. Predisposing factors include skin abrasions, lacerations, burns, eczematous skin, chickenpox, etc. although the portal of entry of organisms is often not seen

 

Wound infection is a localized defect that occurs when the microorganism grow within the damaged skin of a wound. Pain, swelling and redness are the most common symptoms that are accompanied with wound infection. Fever, nausea and chillness are the symptoms of severe wound infection. Redness(caused due to increased blood flow) that appear around the wound is considered to be normal inflammatory process of healing. But the existence of redness is an indication wound infection. Immune system get triggered and cause inflammation(increased movement of white blood cells and fluids) in response to wound infection.

 

Microorganisms like Streptococcus pyogenes, Enterococci, Staphylococcus aureus and Pseudomonas aeruginosa are the major causative agent for wound infections. Genes responsible for causing infection various among microorganism. TSST-1 of the staphylococcus aureus bind to the HLA II DR1 molecule and are involved in the development of S. aureus bacteremia and endocarditis. MSCRAMMs (Fms8) Genes are responsible for facilitating the binding of host cells and colonization. SCG2 and MG53(present in human) are involved in helping the body to fix injury in the skin.

 

Immunosupression is a condition in which the body’s immune system get suppressed to fight against the infection and other diseases. It should be induced with the consumption or administration of drugs such as azathioprine, corticosteroids, specific antibody etc. Immunosupressive therapies are used to lower the body immune reactivity against transplantes tissues or organs. Increased risk of infection is considered to be the most important side effect of immunosuppressant drugs. It happen by destroying much of the immune cells and making the patient vulnerable to infection.

 

 

 

Wound infection is a localized defect that occurs when the microorganism grow within the damaged skin of a wound. Pain, swelling and redness are the most common symptoms that are accompanied with wound infection. Fever, nausea and chillness are the symptoms of severe wound infection. Redness(caused due to increased blood flow) that appear around the wound is considered to be normal inflammatory process of healing. But the existence of redness is an indication wound infection. Immune system get triggered and cause inflammation(increased movement of white blood cells and fluids) in response to wound infection.

 

Microorganisms like Streptococcus pyogenes, Enterococci, Staphylococcus aureus and Pseudomonas aeruginosa are the major causative agent for wound infections. Genes responsible for causing infection various among microorganism. TSST-1 of the staphylococcus aureus bind to the HLA II DR1 molecule and are involved in the development of S. aureus bacteremia and endocarditis. MSCRAMMs (Fms8) Genes are responsible for facilitating the binding of host cells and colonization. SCG2 and MG53(present in human) are involved in helping the body to fix injury in the skin.

 

Immunosupression is a condition in which the body’s immune system get suppressed to fight against the infection and other diseases. It should be induced with the consumption or administration of drugs such as azathioprine, corticosteroids, specific antibody etc. Immunosupressive therapies are used to lower the body immune reactivity against transplantes tissues or organs. Increased risk of infection is considered to be the most important side effect of immunosuppressant drugs. It happen by destroying much of the immune cells and making the patient vulnerable to infection.

 

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